IGHG1 Recombinant Monoclonal Antibody

Code CSB-RA011156MA4HU
Size US$210
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  • Western Blot
    Positive WB detected in: U251 whole cell lysate(30µg)
    All lanes: IGHG1 antibody at 1:1000
    Secondary
    Goat polyclonal to Human IgG at 1/40000 dilution
    Predicted band size: 36 kDa
    Observed band size:36 kDa
    Exposure time: 3min
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Product Details

Uniprot No.
Target Names
IGHG1
Alternative Names
IGHG1 antibody; Immunoglobulin heavy constant gamma 1 antibody; Ig gamma-1 chain C region antibody; Ig gamma-1 chain C region EU antibody; Ig gamma-1 chain C region KOL antibody; Ig gamma-1 chain C region NIE antibody
Species Reactivity
Human
Immunogen
Recombinant Human IGHG1 protein
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Monoclonal
Isotype
hIgG1
Clone No.
9E7
Purification Method
Affinity-chromatography
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.
Involvement in disease
Multiple myeloma (MM)
Subcellular Location
Secreted. Cell membrane.
Database Links

HGNC: 5525

OMIM: 147100

UniGene: Hs.510635

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China
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