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| Code | CSB-RA958367A0HU |
| Size | US$350 |
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| Have Questions? | Leave a Message or Start an on-line Chat |
| Uniprot No. | Q8NB78 | ||||
| Target Names | KDM1B | ||||
| Alternative Names |
Lysine-specific histone demethylase 1B (EC 1.-.-.-) (Flavin-containing amine oxidase domain-containing protein 1) (Lysine-specific histone demethylase 2), KDM1B, AOF1 C6orf193 LSD2
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| Species Reactivity | Human | ||||
| Immunogen | A synthesized peptide derived from human KDM1B | ||||
| Immunogen Species | Homo sapiens (Human) | ||||
| Conjugate | Non-conjugated | ||||
| Clonality | Monoclonal | ||||
| Isotype | Rabbit IgG | ||||
| Clone No. | 15F3 | ||||
| Purification Method | Affinity-chromatography | ||||
| Concentration | It differs from different batches. Please contact us to confirm it. | ||||
| Buffer | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | ||||
| Form | Liquid | ||||
| Tested Applications | ELISA, WB | ||||
| Recommended Dilution |
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| Protocols | ELISA Protocol Western Blotting(WB) Protocol |
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| Troubleshooting and FAQs | Antibody FAQs | ||||
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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| Function |
Histone demethylase that demethylates 'Lys-4' of histone H3, a specific tag for epigenetic transcriptional activation, thereby acting as a corepressor. Required for de novo DNA methylation of a subset of imprinted genes during oogenesis. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Demethylates both mono- and di-methylated 'Lys-4' of histone H3. Has no effect on tri-methylated 'Lys-4', mono-, di- or tri-methylated 'Lys-9', mono-, di- or tri-methylated 'Lys-27', mono-, di- or tri-methylated 'Lys-36' of histone H3, or on mono-, di- or tri-methylated 'Lys-20' of histone H4.
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| Gene References into Functions |
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| Subcellular Location | Nucleus. |
| Protein Families | Flavin monoamine oxidase family |
| Database Links |
HGNC: 21577 OMIM: 613081 KEGG: hsa:221656 STRING: 9606.ENSP00000297792 UniGene: Hs.709336 |
