Code | CSB-RA582749A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IHC | 1:50-1:200 |
The KRT10 recombinant monoclonal antibody production is a meticulously coordinated process. It commences with in vitro cloning, where KRT10 antibody genes are seamlessly incorporated into expression vectors. Subsequently, these vectors are introduced into host cells, facilitating the recombinant antibody's expression within a cell culture environment. Following expression, the KRT10 recombinant monoclonal antibody undergoes purification from the supernatant of transfected host cell lines through an affinity-chromatography purification method. This antibody only recognizes the human KRT10 protein. It has been tested for ELISA and IHC applications.
KRT10 plays a central role in maintaining the structural integrity of the epidermis, contributing to the formation of a protective skin barrier, and facilitating the process of epidermal differentiation and cornification. Its proper function is essential for healthy skin, and mutations in the KRT10 gene can lead to skin disorders characterized by skin fragility and abnormalities.
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