Code | CSB-RA551427A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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WB | 1:500-1:2000 |
FC | 1:50-1:200 |
The MAP1LC3B recombinant monoclonal antibody is generated via a meticulously executed process. It initiates with in vitro cloning, where genes encoding both the heavy and light chains of the MAP1LC3B antibody are incorporated into expression vectors, which are subsequently introduced into host cells, setting the stage for the recombinant antibody's expression within a cell culture environment. Following expression, the MAP1LC3B recombinant monoclonal antibody undergoes purification from the supernatant of transfected host cell lines, relying on the precision of affinity chromatography. An outstanding attribute of this antibody is its specific binding affinity for the human MAP1LC3B protein. Additionally, it is known for its versatility, making it suitable for an array of applications, including ELISA, WB, and FC.
MAP1LC3B is a critical protein in the autophagy pathway, where it plays a central role in autophagosome formation, cargo recognition, and autophagosome-lysosome fusion. It is also involved in quality control mechanisms within cells. MAP1LC3B helps remove damaged organelles, misfolded proteins, and protein aggregates, contributing to the maintenance of cellular health and preventing the accumulation of potentially harmful materials.
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