Code | CSB-RA181189A0HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
WB | 1:500-1:5000 |
IHC | 1:50-1:200 |
FC | 1:20-1:200 |
NKX2-1 is a homeodomain transcription factor that is required for thyroid genesis and thyroid-specific gene transcription. NKX2-1 is selectively expressed from prenatal development to adulthood in the brain, thyroid gland, parathyroid gland, lungs, skin, and enteric ganglia, and plays a vital role at the interface of the brain, endocrine, and immune systems. NKX2-1 is involved in a number of physiologic processes that are linked to the somatic symptoms that are typical in schizophrenia. NKX2-1 is also important for neurodevelopment and is required for the formation and function of subgroups of neurons, glia, and functional brain networks in schizophrenia.
The production of the recombinant NKX2-1 antibody includes extracting RNA from spleen cells that are derived from immunized animals, reversely transcribing the RNA into DNA, sequencing and screening antibody genes, amplifying the heavy chain and light chain genes of the antibody using PCR technology, linking and cloning the genes into a plasma vector, and introducing the vector clone into a mammalian cell for functional antibody expression. The recombinant NKX2-1 antibody was purified using Affinity-chromatography. It can be used to detect the NKX2-1 antibody from Human in the ELISA, WB, IHC, FC.There are currently no reviews for this product.