Code | CSB-RA198162A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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IHC | 1:50-1:200 |
The production of the PTK2 recombinant monoclonal antibody involves the harvest of the PTK2 monoclonal antibody, sequencing its gene, constructing a vector that contains the PTK2 monoclonal antibody, and transfecting the plasmid vector into a host cell line. The immunogen for the PTK2 monoclonal antibody is a synthesized peptide derived from human PTK2. The PTK2 recombinant monoclonal antibody is purified from the cell culture supernatant using affinity chromatography. The specificity of this antibody is tested in ELISA and IHC applications. It only reacts with human PTK2 protein.
The PTK2 protein, also known as focal adhesion kinase (FAK), is a cytoplasmic tyrosine kinase that plays critical roles in regulating cell adhesion, migration, proliferation, and survival. PTK2 is involved in the regulation of cell migration by regulating the formation and turnover of focal adhesions. PTK2 activation can lead to the phosphorylation of downstream targets that regulate actin cytoskeleton dynamics and cell motility. PTK2 plays a role in the regulation of cell proliferation by regulating cell cycle progression and cell survival. PTK2 activation has been shown to promote cell cycle progression by regulating the activity of cyclin-dependent kinases and downstream signaling pathways. Dysregulation of PTK2 activity has been implicated in various diseases, including cancer, cardiovascular disease, and neurological disorders.
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