Code | CSB-RA567944A0HU |
Size | US$210 |
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Application | Recommended Dilution |
---|---|
WB | 1:500-1:2000 |
IHC | 1:50-1:200 |
The PVR recombinant monoclonal antibody undergoes a comprehensive production process, commencing with in vitro cloning, where genes encoding the PVR antibody's heavy and light chains are incorporated into expression vectors. Subsequently, these vectors are transfected into host cells to enable recombinant antibody expression within a cell culture system. Post-expression, the PVR recombinant monoclonal antibody is purified from the supernatant of transfected host cell lines, employing an affinity-chromatography purification technique. An important feature of this antibody is its specific binding capability with the human PVR protein. Furthermore, its versatility shines through as it is suitable for diverse applications, encompassing ELISA, WB, and IHC.
The poliovirus receptor (PVR), also known as the CD155 receptor, mainly serves as a cell surface receptor for poliovirus and related enteroviruses. It plays a critical role in the initial attachment and entry of the virus into host cells.
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