Recombinant Human B2 bradykinin receptor(BDKRB2)

Code CSB-CF002652HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P30411
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence MFSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQPPFLWVLFVLATLENIFVLSVFCLHKSSCTVAEIYLGNLAAADLILACGLPFWAITISNNFDWLFGETLCRVVNAIISMNLYSSICFLMLVSIDRYLALVKTMSMGRMRGVRWAKLYSLVIWGCTLLLSSPMLVFRTMKEYSDEGHNVTACVISYPSLIWEVFTNMLLNVVGFLLPLSVITFCTMQIMQVLRNNEMQKFKEIQTERRATVLVLVVLLLFIICWLPFQISTFLDTLHRLGILSSCQDERIIDVITQIASFMAYSNSCLNPLVYVIVGKRFRKKSWEVYQGVCQKGGCRSEPIQMENSMGTLRTSISVERQIHKLQDWAGSRQ
Source in vitro E.coli expression system
Gene Names BDKRB2
Protein Names Recommended name: B2 bradykinin receptor Short name= B2R Short name= BK-2 receptor
Expression Region 1-391
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Receptor for bradykinin. It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system.
Subcellular Location Cell membrane, Multi-pass membrane protein
Protein Families G-protein coupled receptor 1 family, Bradykinin receptor subfamily, BDKRB2 sub-subfamily
Tissue Specificity Ubiquitous. Widespread in normal smooth muscle tissue and neurons.
Database Links

HGNC: 1030

OMIM: 113503

KEGG: hsa:624

STRING: 9606.ENSP00000307713

UniGene: Hs.654542

Pathway Calcium signaling pathway
Regulation of actin cytoskeleton
Complement and coagulation cascades
cGMP-PKG signaling pathway
Sphingolipid signaling pathway

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