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| Code | CSB-CF007972HU |
| Product Type | Transmembrane Protein |
| Size | Pls inquiry other sizes |
| Uniprot No. | O60667 |
| Storage Buffer | Tris-based buffer,50% glycerol |
| Species | Homo sapiens (Human) |
| Sequence | RILPEVKVEGELGGSVTIKCPLPEMHVRIYLCREMAGSGTCGTVVSTTNFIKAEYKGRVTLKQYPRKNLFLVEVTQLTESDSGVYACGAGMNTDRGKTQKVTLNVHSEYEPSWEEQPMPETPKWFHLPYLFQMPAYASSSKFVTRVTTPAQRGKVPPVHHSSPTTQITHRPRVSRASSVAGDKPRTFLPSTTASKISALEGLLKPQTPSYNHHTRLHRQRALDYGSQSGREGQGFHILIPTILGLFLLALLGLVVKRAVERRKALSRRARRLAVRMRALESSQRPRGSPRPRSQNNIYSACPRRARGADAAGTGEAPVPGPGAPLPPAPLQVSESPWLHAPSLKTSCEYVSLYHQPAAMMEDSDSDDYINVPA |
| Source | in vitro E.coli expression system |
| Gene Names | FCMR |
| Protein Names | Recommended name: Fas apoptotic inhibitory molecule 3 Alternative name(s): Regulator of Fas-induced apoptosis Toso |
| Expression Region | 18-390 |
| Tag Info | N-terminal 10xHis-tagged |
| Protein Description | Full Length of Mature Protein |
| Storage | Store at -20°C, for extended storage, conserve at -20°C or -80°C. |
| Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation. |
| Subcellular Location | Isoform 1: Membrane, Single-pass membrane protein, SUBCELLULAR LOCATION: Isoform 3: Secreted |
| Tissue Specificity | Expressed in lymph nodes, peripheral blood leukocytes, lung, thymus and kidneys. Very weak expression detected in spleen, liver, heart, and salivary gland. Expressed in lymphoid cell lines such as Jurkat, CEM-T4, MOLT-4, HB11;19 and Reh. No expression det |
| Database Links |
HGNC: 14315 OMIM: 606015 KEGG: hsa:9214 STRING: 9606.ENSP00000356058 UniGene: Hs.58831 |
FCMR Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA007972ESR2HU | FCMR Antibody | Human | ELISA, IHC |
FCMR Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA127416 | FAIM3 Antibody | Human | ELISA,WB,IHC |
| CSB-PA890678 | FAIM3 Antibody | Human | ELISA,WB |
FCMR Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP007972HU1 CSB-EP007972HU1 CSB-BP007972HU1 CSB-MP007972HU1 |
Recombinant Human Fas apoptotic inhibitory molecule 3(FAIM3),partial | Yeast E.coli Baculovirus Mammalian cell |
FCMR ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL007972HU | Human Fas apoptotic inhibitory molecule 3(FAIM3) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 6.25 pg/mL |
Recombinant Human HLA class I histocompatibility antigen, alpha chain G(HLA-G)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 1(CEACAM1),partial
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human Arylamine N-acetyltransferase 2(NAT2)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Bovine T-cell surface glycoprotein CD8 alpha chain(CD8A),partial
Express system: Yeast
Species: Bos taurus (Bovine)
Recombinant Mouse Asialoglycoprotein receptor 2 (Asgr2),partial
Express system: E.coli
Species: Mus musculus (Mouse)
