Recombinant Human Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA(MAN1A1)

Code CSB-CF013383HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P33908
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence MPVGGLLPLFSSPAGGVLGGGLGGGGGRKGSGPAALRLTEKFVLLLVFSAFITLCFGAIFFLPDSSKLLSGVLFHSSPALQPAADHKPGPGARAEDAAEGRARRREEGAPGDPEAALEDNLARIRENHERALREAKETLQKLPEEIQRDILLEKKKVAQDQLRDKAPFRGLPPVDFVPPIGVESREPADAAIREKRAKIKEMMKHAWNNYKGYAWGLNELKPISKGGHSSSLFGNIKGATIVDALDTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYLSGEEIFRKKAVELGVKLLPAFHTPSGIPWALLNMKSGIGRNWPWASGGSSILAEFGTLHLEFMHLSHLSGNPIFAEKVMNIRTVLNKLEKPQGLYPNYLNPSSGQWGQHHVSVGGLGDSFYEYLLKAWLMSDKTDLEAKKMYFDAVQAIETHLIRKSSSGLTYIAEWKGGLLEHKMGHLTCFAGGMFALGADAAPEGMAQHYLELGAEIARTCHESYNRTFMKLGPEAFRFDGGVEAIATRQNEKYYILRPEVMETYMYMWRLTHDPKYRKWAWEAVEALENHCRVNGGYSGLRDVYLLHESYDDVQQSFFLAETLKYLYLIFSDDDLLPLEHWIFNSEAHLLPILPKDKKEVEIREE
Source in vitro E.coli expression system
Gene Names MAN1A1
Protein Names Recommended name: Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA EC= 3.2.1.113Alternative name(s): Man(9)-alpha-mannosidase Short name= Man9-mannosidase Mannosidase alpha class 1A member 1 Processing alpha-1,2-mannosidase IA Short name= Alpha
Expression Region 1-653
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).
Subcellular Location Golgi apparatus membrane, Single-pass type II membrane protein
Protein Families Glycosyl hydrolase 47 family
Database Links

HGNC: 6821

OMIM: 604344

KEGG: hsa:4121

STRING: 9606.ENSP00000357453

UniGene: Hs.102788

Pathway Protein processing in endoplasmic reticulum

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