Recombinant Human NKG2-C type II integral membrane protein(KLRC2)

Code CSB-CF012467HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P26717
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence MSKQRGTFSEVSLAQDPKRQQRKPKGNKSSISGTEQEIFQVELNLQNPSLNHQGIDKIYDCQGLLPPPEKLTAEVLGIICIVLMATVLKTIVLIPFLEQNNSSPNTRTQKARHCGHCPEEWITYSNSCYYIGKERRTWEESLLACTSKNSSLLSIDNEEEMKFLASILPSSWIGVFRNSSHHPWVTINGLAFKHKIKDSDNAELNCAVLQVNRLKSAQCGSSMIYHCKHKL
Source in vitro E.coli expression system
Gene Names KLRC2
Protein Names Recommended name: NKG2-C type II integral membrane protein Alternative name(s): CD159 antigen-like family member C NK cell receptor C NKG2-C-activating NK receptor CD_antigen= CD159c
Expression Region 1-231
Tag Info 10xHis-SUMO-tag
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
Subcellular Location Membrane, Single-pass type II membrane protein
Tissue Specificity Natural killer cells.
Database Links

HGNC: 6375

OMIM: 602891

KEGG: hsa:3822

STRING: 9606.ENSP00000371327

UniGene: Hs.591157

Pathway Antigen processing and presentation
Natural killer cell mediated cytotoxicity

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