Recombinant Human Platelet glycoprotein V(GP5)

Code CSB-CF009688HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P40197
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Sequence QPFPCPPACKCVFRDAAQCSGGDVARISALGLPTNLTHILLFGMGRGVLQSQSFSGMTVLQRLMISDSHISAVAPGTFSDLIKLKTLRLSRNKITHLPGALLDKMVLLEQLFLDHNALRGIDQNMFQKLVNLQELALNQNQLDFLPASLFTNLENLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHIRSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFLHSHNLTLLTLFENPLAELPGVLFGEMGGLQELWLNRTQLRTLPAAAFRNLSRLRYLGVTLSPRLSALPQGAFQGLGELQVLALHSNGLTALPDGLLRGLGKLRQVSLRRNRLRALPRALFRNLSSLESVQLDHNQLETLPGDVFGALPRLTEVLLGHNSWRCDCGLGPFLGWLRQHLGLVGGEEPPRCAGPGAHAGLPLWALPGGDAECPGPRGPPPRPAADSSSEAPVHPALAPNSSEPWVWAQPVTTGKGQDHSPFWGFYFLLLAVQAMITVIIVFAMIKIGQLFRKLIRERALG
Source in vitro E.coli expression system
Gene Names GP5
Protein Names Recommended name: Platelet glycoprotein V Short name= GPV Alternative name(s): Glycoprotein 5 CD_antigen= CD42d
Expression Region 17-560
Tag Info N-terminal 10xHis-tagged
Protein Description Full Length of Mature Protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis.
Subcellular Location Membrane, Single-pass type I membrane protein
Tissue Specificity Platelets and megakaryocytes.
Database Links

HGNC: 4443

OMIM: 173511

KEGG: hsa:2814

STRING: 9606.ENSP00000319286

UniGene: Hs.73734

Pathway Hematopoietic cell lineage

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