GP5 Antibody

Code CSB-PA006196
Size US$100
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  • Western Blot analysis of Hela cells using CD42d Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
Alternative Names
GP5; Platelet glycoprotein V; GPV; Glycoprotein 5; CD antigen CD42d
Raised in
Species Reactivity
Synthesized peptide derived from the Internal region of Human CD42d.
Immunogen Species
Homo sapiens (Human)
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
It differs from different batches. Please contact us to confirm it.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Tested Applications
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

The GPIb-V-IX complex functions as the vWF receptor and mediates vWF-dependent platelet adhesion to blood vessels. The adhesion of platelets to injured vascular surfaces in the arterial circulation is a critical initiating event in hemostasis.
Gene References into Functions
  1. Raft association and cytoskeletal linkage of the platelet GPIb-IX-V complex are interrelated, and are required for optimal receptor function by attracting signaling proteins and membrane skeletal association allows proteins to move to new locations. PMID: 19874464
  2. Both the high affinity thrombin receptor (GPIb-IX-V) and GPIIb/IIIa are implicated in expression of thrombin-induced platelet procoagulant activity. PMID: 11686325
  3. GPV is cleaved upon agonist-induced platelet activation, with ADAM17 as the major enzyme mediating this process PMID: 15691827
Subcellular Location
Membrane; Single-pass type I membrane protein.
Tissue Specificity
Platelets and megakaryocytes.
Database Links

HGNC: 4443

OMIM: 173511

KEGG: hsa:2814

STRING: 9606.ENSP00000319286

UniGene: Hs.73734

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