Recombinant Mouse Tumor necrosis factor receptor superfamily member 11A(Tnfrsf11a)

Code CSB-CF023968MO
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. O35305
Storage Buffer Tris-based buffer,50% glycerol
Species Mus musculus (Mouse)
Sequence VTPPCTQERHYEHLGRCCSRCEPGKYLSSKCTPTSDSVCLPCGPDEYLDTWNEEDKCLLHKVCDAGKALVAVDPGNHTAPRRCACTAGYHWNSDCECCRRNTECAPGFGAQHPLQLNKDTVCTPCLLGFFSDVFSSTDKCKPWTNCTLLGKLEAHQGTTESDVVCSSSMTLRRPPKEAQAYLPSLIVLLLFISVVVVAAIIFGVYYRKGGKALTANLWNWVNDACSSLSGNKESSGDRCAGSHSATSSQQEVCEGILLMTREEKMVPEDGAGVCGPVCAAGGPWAEVRDSRTFTLVSEVETQGDLSRKIPTEDEYTDRPSQPSTGSLLLIQQGSKSIPPFQEPLEVGENDSLSQCFTGTESTVDSEGCDFTEPPSRTDSMPVSPEKHLTKEIEGDSCLPWVVSSNSTDGYTGSGNTPGEDHEPFPGSLKCGPLPQCAYSMGFPSEAAASMAEAGVRPQDRADERGASGSGSSPSDQPPASGNVTGNSNSTFISSGQVMNFKGDIIVVYVSQTSQEGPGSAEPESEPVGRPVQEETLAHRDSFAGTAPRFPDVCATGAGLQEQGAPRQKDGTSRPVQEQGGAQTSLHTQGSGQCAE
Source in vitro E.coli expression system
Gene Names Tnfrsf11a
Protein Names Recommended name: Tumor necrosis factor receptor superfamily member 11A Alternative name(s): Osteoclast differentiation factor receptor Short name= ODFR Receptor activator of NF-KB CD_antigen= CD265
Expression Region 31-625
Tag Info N-terminal 10xHis-tagged
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells.
Subcellular Location Cell membrane, Single-pass type I membrane protein
Tissue Specificity Ubiquitous expression with high levels in trabecular bone, thymus, small intestine, lung, brain and kidney. Weakly expressed in spleen and bone marrow.
Database Links

KEGG: mmu:21934

STRING: 10090.ENSMUSP00000027559

UniGene: Mm.6251

Pathway NF-kappa B signaling pathway
Osteoclast differentiation

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