CIDEB Antibody

Datasheet

Code	CSB-PA596246
Size	US$297
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Image	Western blot analysis of extracts from RAW264.7 cells and HT-29 cells, using CIDEB antibody. Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue using CIDEB antibody. Immunofluorescence analysis of COS-7 cells, using CIDEB antibody.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CIDEB Polyclonal antibody

Uniprot No.

Q9UHD4

Target Names

CIDEB

Alternative Names

Cell death activator CIDE B antibody; Cell death activator CIDE-B antibody; Cell death inducing DFFA like effector B antibody; Cell death-inducing DFFA-like effector B antibody; CIDEB antibody; CIDEB_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthesized peptide derived from internal of Human CIDEB.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,WB,IHC,IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:3000
IHC	1:50-1:100
IF	1:100-1:500

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Activates apoptosis.; (Microbial infection) Involved in Hepatatis C virus (HCV) assembly and required for HCV entry into hepatocytes.

Gene References into Functions

High Cideb expression is associated with Ulcerative Colitis. PMID: 28719542
CIDEB interacts with the HCV NS5A protein, and the N terminus of CIDEB and the domain I of NS5A are involved in this interaction. PMID: 27282740
these data revealed that Cideb plays an important role in controlling intestinal chylomicron lipidation. PMID: 24831470
this study shows that C5a signaling induces apoptosis in brain vascular endothelial cells in experimental lupus through activation of CIDEB PMID: 27213693
CIDEB downregulation may contribute to HCV-induced hepatic steatosis PMID: 26865724
CIDEB can act as an anti-HCV host factor and contribute to altered triglyceride homeostasis. PMID: 24980280
Authors found CIDEB to be an essential cofactor for hepatitis C virus entry into hepatocytes. PMID: 24829338
this work highlights CIDEB's role in lipid droplet (LD) fusion, and presents a new model system to study the PGC-1alpha/CIDEB pathway's role in LD dynamics and the VLDL pathway. PMID: 24161736
CIDE proteins expression correlate with tumor and survival characteristics in patients with renal cell carcinoma. PMID: 23475172
A novel mechanism for the cell-specific transcription of the human CIDE-B gene, which involves epigenetic and genetic control at separate respective promoters is reported. PMID: 16248853

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Tissue Specificity

Highly expressed in liver and small intestine and, at lower levels, in colon, kidney and spleen.

Database Links

HGNC: 1977

OMIM: 604441

KEGG: hsa:27141

STRING: 9606.ENSP00000258807

UniGene: Hs.642693

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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