COX16 Antibody

Code CSB-PA241484
Size US$166
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Image
  • The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA241484(COX16 Antibody) at dilution 1/50. (Original magnification: ×200)
  • The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using CSB-PA241484(COX16 Antibody) at dilution 1/50. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
COX16
Alternative Names
C14orf112 antibody; COX16 antibody; COX16 cytochrome c oxidase assembly homolog (S. cerevisiae) antibody; COX16_HUMAN antibody; Cytochrome c oxidase assembly factor antibody; Cytochrome c oxidase assembly protein COX16 homolog antibody; HSPC203 antibody; mitochondrial antibody; PTD019 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human COX16
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:500-1:2000
IHC 1:25-1:100
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Required for the assembly of the mitochondrial respiratory chain complex IV (CIV), also known as cytochrome c oxidase. Promotes the insertion of copper into the active site of cytochrome c oxidase subunit II (MT-CO2/COX2). Interacts specifically with newly synthesized MT-CO2/COX and its copper center-forming metallochaperones SCO1, SCO2 and COA6. Probably facilitates MT-CO2/COX2 association with the MITRAC assembly intermediate containing MT-CO1/COX1, thereby participating in merging the MT-CO1/COX1 and MT-CO2/COX2 assembly lines.
Gene References into Functions
  1. COX16 is required for assembly of cytochrome C oxidase in human cells and is involved in copper delivery to COX2. PMID: 29355485
Subcellular Location
Mitochondrion inner membrane; Single-pass membrane protein.
Protein Families
COX16 family
Tissue Specificity
Widely expressed. Expressed at higher level in skeletal muscle, heart and liver.
Database Links

HGNC: 20213

KEGG: hsa:51241

STRING: 9606.ENSP00000374562

UniGene: Hs.709581

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