CTPS2 Antibody

Datasheet

Code	CSB-PA865117EA01HU
Size	US$166
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Image	Immunoprecipitating CTPS2 in HepG2 whole cell lysate Lane 1: Rabbit control IgG instead of CSB-PA865117EA01HU in HepG2 whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000) Lane 2: CSB-PA865117EA01HU (6µg) + HepG2 whole cell lysate (500µg) Lane 3: HepG2 whole cell lysate (20µg) Western Blot Positive WB detected in: HepG2 whole cell lysate All lanes: CTPS2 antibody at 2.8µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 66 kDa Observed band size: 66 kDa Immunocytochemistry analysis of human gastric cancer using CSB-PA865117EA01HU at dilution of 1:100 Immunocytochemistry analysis of human prostate tissue using CSB-PA865117EA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) CTPS2 Polyclonal antibody

Uniprot No.

Q9NRF8

Target Names

CTPS2

Alternative Names

CTP synthase 2 antibody; CTP synthase II antibody; CTP synthetase 2 antibody; CTPS2 antibody; CYTIDINE 5 PRIME TRIPHOSPHATE SYNTHETASE 2 antibody; FLJ43358 antibody; MGC32997 antibody; PYRG2_HUMAN antibody; UTP--ammonia ligase 2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human CTP synthase 2 protein (62-315AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The CTPS2 Antibody (Product code: CSB-PA865117EA01HU) is Non-conjugated. For CTPS2 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA865117EB01HU	CTPS2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA865117EC01HU	CTPS2 Antibody, FITC conjugated
Biotin	CSB-PA865117ED01HU	CTPS2 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IP

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200
IP	1:200-1:2000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunoprecipitation (IP) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides.

Gene References into Functions

CTPS2 was identified by genome-wide gene expression analyses as correlated with cellular sensitivity to cisplatin and carboplatin. PMID: 21252287
Low CTPS2 expression may be a rationally-based determinant of 5FU resistance. PMID: 21378502
analysis of the kinetic properties of hCTPS1 and hCTPS2, and determination that Ser(68) is a major site of CTPS2 regulation by phosphorylation PMID: 20739275

Protein Families

CTP synthase family

Database Links

HGNC: 2520

OMIM: 300380

KEGG: hsa:56474

STRING: 9606.ENSP00000352222

UniGene: Hs.227049

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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