DAP3 Antibody

Code CSB-PA922061
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA922061(DAP3 Antibody) at dilution 1/15, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 12%SDS-PAGE, Lysate: 30 μg, Lane: Human lymphoma tissue, Primary antibody: CSB-PA922061(DAP3 Antibody) at dilution 1/150, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
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Product Details

Uniprot No.
Target Names
DAP3
Alternative Names
28S ribosomal protein S29 antibody; 28S ribosomal protein S29 mitochondrial antibody; bMRP10 antibody; DAP 3 antibody; DAP-3 antibody; Dap3 antibody; Death associated protein 3 antibody; Death-associated protein 3 antibody; DKFZp686G12159 antibody; FLJ12817 antibody; Ionizing radiation resistance conferring protein antibody; MGC126058 antibody; MGC126059 antibody; Mitochondrial 28S ribosomal protein S29 antibody; mitochondrial antibody; MITOCHONDRIAL RIBOSOMAL PROTEIN S29 antibody; MRP S29 antibody; MRP-S29 antibody; MRPS29 antibody; OTTHUMP00000033480 antibody; OTTHUMP00000033481 antibody; PSD-95/SAP90-binding protein 3 antibody; RT29_HUMAN antibody; S29mt antibody; SAP90/PSD-95-associated protein 3 antibody; SAPAP3 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Fusion protein of Human DAP3
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:5000
WB 1:200-1:1000
IHC 1:10-1:50
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Involved in mediating interferon-gamma-induced cell death.
Gene References into Functions
  1. DAP3 plays important roles in mitochondrial function and dynamics PMID: 26306039
  2. DAP3 silencing contributes to breast carcinogenesis. PMID: 25738636
  3. Knockdown of DAP3 expression promoted cell migration. PMID: 24300973
  4. Study demonstrates an inverse association between DAP3 mRNA levels and tumour stage and clinical outcome in breast cancer. PMID: 22287761
  5. identified a novel DAP3-binding protein termed death ligand signal enhancer (DELE); results demonstrated the biological significance of DELE for apoptosis signal mediated by death receptors PMID: 20563667
  6. show that interferon-beta promoter stimulator 1 (IPS-1) binds DAP3 and induces anoikis by caspase activation. PMID: 19644511
  7. Functional interaction between the pro-apoptotic DAP3 and the glucocorticoid receptor PMID: 12099703
  8. not involved in TRAIL-induced apoptosis PMID: 12359235
  9. DAP3 has a role in the molecular pathway that culminates in fragmented mitochondria PMID: 15175341
  10. DAP3 gene might be associated with the mechanisms responsible for adult bronchial asthma and contribute to airway inflammation and remodeling PMID: 15179560
  11. DAP3 has a role in anoikis signaling and in apoptosis induction caused by cell detachment PMID: 15302871
  12. High DAP3 expression is correlated with thymoma stage PMID: 15679048
  13. study investigated the phosphorylation status of ribosomal DAP3 and mapped the phosphorylation sites by tandem mass spectrometry PMID: 18227431
  14. Complex I and DAP3, hNOA1 may play a role in mitochondrial respiration and apoptosis. PMID: 19103604
  15. DAP3 may participate in mitochondrial maintenance and play a role in the balance between mitochondrial homoeostasis and tumourigenesis in thyroid oncocytic tumors. PMID: 19536094

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Subcellular Location
Mitochondrion.
Protein Families
Mitochondrion-specific ribosomal protein mS29 family
Tissue Specificity
Ubiquitous.
Database Links

HGNC: 2673

OMIM: 602074

KEGG: hsa:7818

STRING: 9606.ENSP00000341692

UniGene: Hs.516746

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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