HS2ST1 Antibody

Code CSB-PA010746LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: Rat spleen tissue
    All lanes: HS2ST1 antibody at 2.7µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 42, 35, 27 kDa
    Observed band size: 42 kDa

  • Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA010746LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA010746LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) HS2ST1 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
2-O-sulfotransferase antibody; 2OST antibody; dJ604K5.2 antibody; FLJ11317 antibody; heparan sulfate 2 O sulfotransferase 1 antibody; Heparan sulfate 2-O-sulfotransferase 1 antibody; HS2ST_HUMAN antibody; hs2st1 antibody; KIAA0448 antibody; MGC131986 antibody
Raised in
Rabbit
Species Reactivity
Human, Rat
Immunogen
Recombinant Human Heparan sulfate 2-O-sulfotransferase 1 protein (29-229AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The HS2ST1 Antibody (Product code: CSB-PA010746LA01HU) is Non-conjugated. For HS2ST1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA010746LB01HU HS2ST1 Antibody, HRP conjugated ELISA
FITC CSB-PA010746LC01HU HS2ST1 Antibody, FITC conjugated
Biotin CSB-PA010746LD01HU HS2ST1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Catalyzes the transfer of sulfate to the C2-position of selected hexuronic acid residues within the maturing heparan sulfate (HS). 2-O-sulfation within HS, particularly of iduronate residues, is essential for HS to participate in a variety of high-affinity ligand-binding interactions and signaling processes. Mediates 2-O-sulfation of both L-iduronyl and D-glucuronyl residues.
Gene References into Functions
  1. C5-epimerase and 2-O-sulfotransferase in association generate extended domains of consecutive GlcNS-IdoA2S Sequence. PMID: 25594747
  2. analysis of differences and similarities various residues play in the biological roles of the HS-2OST and CS-2OST enzymes PMID: 17227754
Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein.
Protein Families
Sulfotransferase 3 family
Database Links

HGNC: 5193

OMIM: 604844

KEGG: hsa:9653

STRING: 9606.ENSP00000359581

UniGene: Hs.743280

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