SPATA16 Antibody

Datasheet

Code	CSB-PA871597LA01HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA871597LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA871597LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) SPATA16 Polyclonal antibody

Uniprot No.

Q9BXB7

Target Names

SPATA16

Alternative Names

NYD SP12 antibody; NYD-SP12 antibody; NYDSP12 antibody; SPATA16 antibody; Spermatogenesis associated 16 antibody; Spermatogenesis-associated protein 16 antibody; SPGF6 antibody; SPT16_HUMAN antibody; Testis development protein antibody; Testis development protein NYD-SP12 antibody; Testis specific Golgi protein antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Spermatogenesis-associated protein 16 protein (238-475AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The SPATA16 Antibody (Product code: CSB-PA871597LA01HU) is Non-conjugated. For SPATA16 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA871597LB01HU	SPATA16 Antibody, HRP conjugated	ELISA
FITC	CSB-PA871597LC01HU	SPATA16 Antibody, FITC conjugated
Biotin	CSB-PA871597LD01HU	SPATA16 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Involved in the formation of sperm acrosome, which implicated its potential role in spermatogenesis and sperm-egg fusion.

Gene References into Functions

This study demonstrates that Spata16 is indispensable for male fertility in mice, as well as in humans. PMID: 29065458
Mutation of SPATA16 is associated with globozoospermia. PMID: 27086357
Case Report: report of a pregnancy obtained in a man with homozygous SPATA16 mutated globozoospermia. PMID: 24825417
results suggest that NYD-SP12 is involved in spermatogenesis, and that NYD-SP12-encoded protein might function in the Golgi apparatus PMID: 12529416
study demonstrated NYD-SP12 protein was involved in the formation of the acrosome during spermatogenesis PMID: 16372119
Results indicate that NYD-SP12 evolves rapidly in both the human and the chimpanzee lineages, which is likely caused by Darwinian positive selection and/or sexual selection. PMID: 17665087
consanguineous family with three affected brothers, in whom we have identified a homozygous mutation in the spermatogenesis-specific gene SPATA16. This is the first example of a nonsyndromic male infertility condition caused by an autosomal gene defect. PMID: 17847006

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Involvement in disease

Spermatogenic failure 6 (SPGF6)

Subcellular Location

Golgi apparatus. Note=Localized to the perinuclear region.

Protein Families

SPATA16 family

Tissue Specificity

Expressed in testis.

Database Links

HGNC: 29935

OMIM: 102530

KEGG: hsa:83893

STRING: 9606.ENSP00000341765

UniGene: Hs.444236

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Email: [email protected]
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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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