Recombinant Human Thymic stromal lymphopoietin protein(TSLP) (Active)

In Stock
Code CSB-AP002121HU
Product Type Colony Stimulating Factor
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. Q969D9
Lead Time 5-10 business days
Image
Storage Buffer 0.2 μm filtered 20 mM PB, pH 7.4, 150 mM NaCl ,lyophilized
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human IL-7Rα and human TSLP R co-transfected murine BaF3 pro-B cells is less than 0.3 ng/ml, corresponding to a specific activity of >3.3x106 IU/mg.
Purity >98% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence M+YDFTNCDFE KIKAAYLSTI SKDLITYMSG TKSTEFNNTV SCSNRPHCLT EIQSLTFNPT AGCASLAKEM FAMKTKAALA IWCPGYSETQ INATQAMKKR RKRKVTTNKC LEQVSQLQGL WRRFNRPLLK QQ
Research Area Immunology
Source E.coli
Gene Names TSLP
Expression Region 29-159aa
Tag Info Tag-Free
Mol. Weight 15.1 kDa
Protein Description Full Length of Mature Protein
PubMed ID 11418668; 11480573; 15372022; 15489334; 17242164; 24850429
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Function Isoform 1
Subcellular Location Secreted
Tissue Specificity Isoform 1 is expressed in a number of tissues including heart, liver and prostate. Isoform 2 is the predominant form in keratinocytes of oral mucosa, skin and in salivary glands. It is secreted into saliva.
Database Links

HGNC: 30743

OMIM: 607003

KEGG: hsa:85480

STRING: 9606.ENSP00000339804

UniGene: Hs.389874

Pathway Jak-STAT signaling pathway

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