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| Code | CSB-AP003451MO |
| Product Type | Colony Stimulating Factor |
| Size |
US$112Purchase it in Cusabio online store (only available for customers from the US) |
| Uniprot No. | P40226 |
| Lead Time | 5-10 business days |
| Image | |
| Storage Buffer | 0.2 μm filtered PBS, pH 7.4, with 5% Trehalose ,lyophilized |
| Alias | C-mpl ligand, Megakaryocyte colony-stimulating factor, Megakaryocyte growth and development factor, MGDF, Myeloproliferative leukemia virus oncogene ligand |
| Species | Mus musculus (Mouse) |
| Biological_Activity | Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human MO7e cells is less than 1.0 ng/ml, corresponding to a specific activity of >1.0x106 IU/mg. |
| Purity | >95% as determined by SDS-PAGE and HPLC. |
| Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
| Sequence | SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF |
| Research Area | Cancer |
| Source | E.coli |
| Gene Names | Thpo |
| Expression Region | 22-195aa |
| Tag Info | Tag-Free |
| Mol. Weight | 18.7 kDa |
| Protein Description | Partial |
| PubMed ID | 8202158; 8020099; 7849319; 15489334; 22284746 |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets. |
| Subcellular Location | Secreted |
| Protein Families | EPO/TPO family |
| Tissue Specificity | Found mainly in the liver, kidney and skeletal muscle. |
| Database Links |
KEGG: mmu:21832 STRING: 10090.ENSMUSP00000075756 UniGene: Mm.3943 |
| Pathway |
Jak-STAT signaling pathway
Hematopoietic cell lineage |
Thpo Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP023509MO CSB-EP023509MO CSB-BP023509MO CSB-MP023509MO |
Recombinant Mouse Thrombopoietin(Thpo) | Yeast E.coli Baculovirus Mammalian cell |
Thpo ELISA Kit for Mus musculus (Mouse)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E04746m | Mouse Thrombopoietin,TPO ELISA kit | serum, plasma, tissue homogenates | 1.56 pg/mL |
Recombinant Mouse Interferon regulatory factor 8(Irf8)
Express system: E.coli
Species: Mus musculus (Mouse)
Recombinant Human Deoxycytidylate deaminase(DCTD)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Human F-box/LRR-repeat protein 2(FBXL2)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Macaca mulatta (Rhesus macaque) Interleukin-1 alpha(IL1A)
Express system: E.coli
Species: Macaca mulatta (Rhesus macaque)
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Recombinant Human Aquaporin-1(AQP1)
Express system: in vitro E.coli expression system
Species: Homo sapiens (Human)
Recombinant Mouse Ras-related protein Rab-10(Rab10)
Express system: E.coli
Species: Mus musculus (Mouse)
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