GHR Antibody

Datasheet
Code CSB-PA009411ZA01PI
Uniprot No. P19756
Delivery Make-to-order
Immunogen Recombinant Pig Growth hormone receptor (GHR), partial (19-264AA)
Raised in Rabbit
Species Reactivity Sus scrofa
Tested Applications ELISA, WB (ensure identification of antigen)
Form Liquid
Conjugate Non-conjugate
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Protein A/G
Isotype IgG
Clonality Polyclonal
Alias Growth hormone receptor (GH receptor) (Somatotropin receptor) [Cleaved into: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)], GHR
Immunogen Species Sus scrofa (Pig)
Protocols ELISA Protocol
Gene Names GHR
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Receptor for pituitary gland growth hormone involved in regulating postnatal body growth. On ligand binding, couples to, and activates the JAK2/STAT5 pathway.; FUNCTION
Subcellular Location Cell membrane, Single-pass type I membrane protein, Note=On growth hormone binding, GHR is ubiquitinated, internalized, down-regulated and transported into a degradative or non-degradative pathway, SUBCELLULAR LOCATION: Growth hormone-binding protein: Secreted
Protein Families Type I cytokine receptor family, Type 1 subfamily
Database Links

STRING: 9823.ENSSSCP00000017873

UniGene: Ssc.93799

Pathway Jak-STAT signaling pathway
PI3K-Akt signaling pathway

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