igf1 Antibody

Code CSB-PA324597XA01FVH
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Product Details

Full Product Name
Rabbit anti-Oncorhynchus kisutch (Coho salmon) (Salmo kisutch) igf1 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
igf1Insulin-like growth factor I antibody; IGF-I antibody; Somatomedin antibody
Raised in
Species Reactivity
Oncorhynchus kisutch (Coho salmon) (Salmo kisutch)
Recombinant Oncorhynchus kisutch (Coho salmon) (Salmo kisutch) igf1 protein
Immunogen Species
Oncorhynchus kisutch (Coho salmon) (Salmo kisutch)
Purification Method
Antigen Affinity Purified
It differs from different batches. Please contact us to confirm it.
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Tested Applications
ELISA, WB (ensure identification of antigen)
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. Acts as a ligand for IGF1R. Binds to the alpha subunit of IGF1R, leading to the activation of the intrinsic tyrosine kinase activity which autophosphorylates tyrosine residues in the beta subunit thus initiatiating a cascade of down-stream signaling events leading to activation of the PI3K-AKT/PKB and the Ras-MAPK pathways. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling.
Subcellular Location
Protein Families
Insulin family
Tissue Specificity
All the isoforms are expressed in embryos, juvenile and adult liver, muscle and brain. At least one isoform is expressed in heart, kidney, testes, ovary, adipose tissue and spleen of juvenile salmon.
Database Links

UniGene: Ssa.40

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