IGF1, or pathway, includes signaling pathways such as PI3K/Akt and Ras/Raf/MEK/ERK, etc. Binding of IGF1 to its receptor promotes the activity of tyrosine kinase in the receptor, which in turn triggers a series of downstream signaling events that affect cell proliferation, differentiation, metabolism and survival. IGF1 has a wide range of biological significance and plays an important role in growth and development, cell survival, wound healing, immune regulation, and other physiological processes.IGF1 has a significant role in promoting cell growth and division through the promotion of protein synthesis, inhibition of protein catabolism, and regulation of the cell cycle. In addition, IGF1 is involved in the regulation of bone growth and remodeling, and influences muscle mass and strength. In disease states, aberrant expression of IGF1 has been associated with a variety of diseases, including certain types of cancer, diabetes, and cardiovascular disease. Thus, IGF1 is a potential target in clinical therapy and drug development.
Recombinant Human Insulin-like growth factor I (IGF1) (CSB-EP356436HUe0)
Validated Data
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-RP065544h could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) IGF1.
Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-RP065544h could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) IGF1.
The following IGF1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
IGF1 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA08399A0Rb | IGF1 Antibody | Human | ELISA, IHC |
CSB-PA08399B0Rb | IGF1 Antibody, HRP conjugated | Human | ELISA |
CSB-PA070545 | IGF1 Antibody | Human | ELISA,IHC |
IGF1 Antibodies for Oncorhynchus kisutch (Coho salmon) (Salmo kisutch)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA324597XA01FVH | igf1 Antibody | Oncorhynchus kisutch (Coho salmon) (Salmo kisutch) | ELISA, WB (ensure identification of antigen) |
IGF1 Antibodies for Ailuropoda melanoleuca (Giant panda)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA740272XA01AYX | IGF1 Antibody | Ailuropoda melanoleuca (Giant panda) | ELISA, WB (ensure identification of antigen) |
IGF1 Antibodies for Rattus norvegicus (Rat)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA076074ZA01RA | Igf1 Antibody | Rattus norvegicus | ELISA, WB (ensure identification of antigen) |
IGF1 Proteins for Ovis aries (Sheep)
Code | Product Name | Source |
---|---|---|
CSB-YP011086SH CSB-EP011086SH CSB-BP011086SH CSB-MP011086SH CSB-EP011086SH-B |
Recombinant Sheep Insulin-like growth factor I (IGF1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1 Proteins for Sus scrofa (Pig)
Code | Product Name | Source |
---|---|---|
CSB-YP011086PI CSB-EP011086PI CSB-BP011086PI CSB-MP011086PI CSB-EP011086PI-B |
Recombinant Pig Insulin-like growth factor I (IGF1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1 Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-BP011086CH CSB-MP011086CH CSB-EP011086CH-B |
Recombinant Chicken Insulin-like growth factor I (IGF1) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1 Proteins for Capra hircus (Goat)
Code | Product Name | Source |
---|---|---|
CSB-YP011086GO CSB-BP011086GO CSB-MP011086GO CSB-EP011086GO-B |
Recombinant Goat Insulin-like growth factor I (IGF1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP011086MO CSB-EP011086MO CSB-BP011086MO CSB-MP011086MO CSB-EP011086MO-B |
Recombinant Mouse Insulin-like growth factor I (Igf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-BP011086BO CSB-MP011086BO CSB-EP011086BO-B |
Recombinant Bovine Insulin-like growth factor I (IGF1) | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-YP011086BO | Recombinant Bovine Insulin-like growth factor I (IGF1) | Yeast |
IGF1 Proteins for Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Code | Product Name | Source |
---|---|---|
CSB-YP312556OEI CSB-EP312556OEI CSB-BP312556OEI CSB-MP312556OEI CSB-EP312556OEI-B |
Recombinant Oncorhynchus mykiss Insulin-like growth factor I (igf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1 Proteins for Cavia porcellus (Guinea pig)
Code | Product Name | Source |
---|---|---|
CSB-YP321545GU CSB-EP321545GU CSB-BP321545GU CSB-MP321545GU CSB-EP321545GU-B |
Recombinant Guinea pig Insulin-like growth factor I (IGF1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1 Proteins for Oncorhynchus kisutch (Coho salmon) (Salmo kisutch)
Code | Product Name | Source |
---|---|---|
CSB-YP324597OBH CSB-EP324597OBH CSB-BP324597OBH CSB-MP324597OBH CSB-EP324597OBH-B |
Recombinant Oncorhynchus kisutch Insulin-like growth factor I (igf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1 Proteins for Canis lupus familiaris (Dog) (Canis familiaris)
Code | Product Name | Source |
---|---|---|
CSB-YP341443DO CSB-EP341443DO CSB-BP341443DO CSB-MP341443DO CSB-EP341443DO-B |
Recombinant Dog Insulin-like growth factor I (IGF1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1 Proteins for Equus caballus (Horse)
Code | Product Name | Source |
---|---|---|
CSB-YP343939HO CSB-EP343939HO CSB-BP343939HO CSB-MP343939HO CSB-EP343939HO-B |
Recombinant Horse Insulin-like growth factor I (IGF1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1 Proteins for Coturnix japonica (Japanese quail) (Coturnix coturnix japonica)
Code | Product Name | Source |
---|---|---|
CSB-YP344720DXJ CSB-EP344720DXJ CSB-BP344720DXJ CSB-MP344720DXJ CSB-EP344720DXJ-B |
Recombinant Coturnix coturnix japonica Insulin-like growth factor I (IGF1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1 Proteins for Homo sapiens (Human)
IGF1 Proteins for Rattus norvegicus (Rat)
Code | Product Name | Source |
---|---|---|
CSB-YP362300RA CSB-BP362300RA CSB-MP362300RA CSB-EP362300RA-B |
Recombinant Rat Insulin-like growth factor I (Igf1) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CSB-EP362300RA | Recombinant Rat Insulin-like growth factor I (Igf1) | E.coli |
IGF1 Proteins for Suncus murinus (Asian house shrew) (Musk shrew)
Code | Product Name | Source |
---|---|---|
CSB-YP632991FPS CSB-EP632991FPS CSB-BP632991FPS CSB-MP632991FPS CSB-EP632991FPS-B |
Recombinant Suncus murinus Insulin-like growth factor I (IGF1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1 Proteins for Rhinopithecus roxellana (Golden snub-nosed monkey) (Pygathrix roxellana)
Code | Product Name | Source |
---|---|---|
CSB-YP734672PGAL CSB-EP734672PGAL CSB-BP734672PGAL CSB-MP734672PGAL CSB-EP734672PGAL-B |
Recombinant Pygathrix roxellana Insulin-like growth factor I (IGF1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1 Proteins for Ailuropoda melanoleuca (Giant panda)
Code | Product Name | Source |
---|---|---|
CSB-YP740272AYX CSB-EP740272AYX CSB-BP740272AYX CSB-MP740272AYX CSB-EP740272AYX-B |
Recombinant Ailuropoda melanoleuca Insulin-like growth factor I (IGF1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1 Proteins for Ailurus fulgens (Lesser panda) (Red panda)
Code | Product Name | Source |
---|---|---|
CSB-YP750356AYY CSB-EP750356AYY CSB-BP750356AYY CSB-MP750356AYY CSB-EP750356AYY-B |
Recombinant Ailurus fulgens Insulin-like growth factor I (IGF1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1 Proteins for Panthera tigris altaica (Siberian tiger)
Code | Product Name | Source |
---|---|---|
CSB-YP756986PHAS CSB-EP756986PHAS CSB-BP756986PHAS CSB-MP756986PHAS CSB-EP756986PHAS-B |
Recombinant Panthera tigris altaica Insulin-like growth factor I (IGF1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1 Proteins for Oryctolagus cuniculus (Rabbit)
Code | Product Name | Source |
---|---|---|
CSB-YP842512RB CSB-EP842512RB CSB-BP842512RB CSB-MP842512RB CSB-EP842512RB-B |
Recombinant Rabbit Insulin-like growth factor I (IGF1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
IGF1 ELISA Kit for Bos taurus (Bovine)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E08893b | Bovine Insulin-like growth factor 1,IGF-1 ELISA Kit |
IGF1 ELISA Kit for Gallus gallus (Chicken)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E09867Ch | Chicken Insulin-like growth factors 1,IGF-1 ELISA Kit | serum, plasma, tissue homogenates | 125 pg/mL |
IGF1 ELISA Kit for Capra hircus (Goat)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E15909G | Goat insulin-like growth factor 1(IGF-1)ELISA Kit | serum, plasma, tissue homogenates | 12.5 ng/ml. |
IGF1 ELISA Kit for Mus musculus (Mouse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E04581m | Mouse Insulin-like growth factor 1,IGF-1 ELISA Kit | serum, plasma, tissue homogenates | 0.151 ng/mL |
IGF1 ELISA Kit for Sus scrofa (Pig)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E06829p | Pig insulin-like growth factors-1,IGF-1 ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates, cell lysates | 1.56 ng/mL |
IGF1 ELISA Kit for Oryctolagus cuniculus (Rabbit)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E06994Rb | Rabbit Insulin-like growth factor 1,IGF-1 ELISA Kit | serum, plasma, tissue homogenates | 0.039 ng/mL |
IGF1 ELISA Kit for Rattus norvegicus (Rat)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E04582r | Rat Insulin-like growth factor 1,IGF-1 ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 0.151 ng/mL |
IGF1 ELISA Kit for Fish
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E12122Fh | Fish Insulin-like growth factors 1,IGF-1 ELISA Kit | serum, plasma, tissue homogenates | 31.25 pg/mL |
IGF1 ELISA Kit for Homo sapiens (Human)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E04580h | Human insulin-like growth factors 1,IGF-1 ELISA Kit | serum, plasma, tissue homogenates | 1.95 ng/mL |
IGF1 ELISA Kit for Monkey
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E13401Mk | Monkey Insulin-like Growth Factor 1(IGF-1) ELISA KIT | serum, plasma | 15.6 ng/mL |
IGF1 ELISA Kit for Ovis aries (Sheep)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-E13753Sh | Sheep insulin-like growth factor 1,IGF-1 ELISA Kit | serum, plasma, tissue homogenates | 3.9 ng/mL |
IGF1 ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL011086DO | Dog insulin-like growth factor 1 (IGF1) ELISA kit | serum, plasma, tissue homogenates | 7.8 ng/mL |
IGF1 ELISA Kit for Equus caballus (Horse)
Code | Product Name | Sample Types | Sensitivity |
---|---|---|---|
CSB-EL011086HO | Horse insulin-like growth factor 1 (IGF1) ELISA kit | serum, plasma, tissue homogenates | 3.12 ng/mL |