INS Antibody

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Code	CSB-PA011742ZA01RB
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Product Details

Full Product Name

Rabbit anti-Oryctolagus cuniculus (Rabbit) INS Polyclonal antibody

Uniprot No.

P01311

Target Names

INS

Alternative Names

Insulin [Cleaved into: Insulin B chain, Insulin A chain], INS

Raised in

Rabbit

Species Reactivity

Oryctolagus cuniculus

Immunogen

Recombinant Oryctolagus cuniculus INS protein

Immunogen Species

Oryctolagus cuniculus (Rabbit)

Conjugate

Non-conjugate

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (12-14 weeks)

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Target Background

Function

Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.

Gene References into Functions

insulin supports early initiation of the mesodermal factor Brachyury and the signalling molecules Wnt3a and Wnt4 as well as the progression of mesoderm formation PMID: 21827825
Data show that type 1 diabetic blastocyst did not express insulin mRNA. PMID: 20631000

Subcellular Location

Secreted.

Protein Families

Insulin family

Database Links

KEGG: ocu:100009181

STRING: 9986.ENSOCUP00000020463

UniGene: Ocu.1810

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Related pathways

HIF-1 signaling pathway MAPK signaling pathway AMPK signaling mTOR signaling pathway PI3K-Akt signaling pathway Ras signaling pathway Autophagy Regulation of actin cytoskeleton Rap1 signaling pathway FoxO signaling pathway Phospholipase D signaling pathway Insulin signaling pathway cGMP-PKG signaling pathway

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INS Antibody

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