SALM Antibody

Datasheet

Code	CSB-PA334615XA01DLU
Size	US$299
Image	Western Blot Positive WB detected in Recombinant protein All lanes: SALM antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 38 kDa Observed band size: 58 kDa
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Product Details

Full Product Name

Rabbit anti-Drosophila melanogaster (Fruit fly) salm Polyclonal antibody

Uniprot No.

P39770

Target Names

salm

Alternative Names

salm antibody; sal antibody; CG6464 antibody; Homeotic protein spalt-major antibody

Raised in

Rabbit

Species Reactivity

Drosophila melanogaster (Fruit fly)

Immunogen

Recombinant Drosophila melanogaster (Fruit fly) SALM protein

Immunogen Species

Drosophila melanogaster (Fruit fly)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Protein A/G

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

The SALM polyclonal antibody is obtained by introducing recombinant Drosophila melanogaster (Fruit fly) SALM protein into a rabbit, which stimulates the production of antibodies that target this particular antigen. Antibody production is further boosted through a booster injection, and the resulting SALM polyclonal antibodies present in the rabbit's serum are collected and purified using protein A/G. Comprehensive testing conducted in ELISA and WB assays has validated the SALM antibody's specific ability to recognize Drosophila melanogaster (Fruit fly) SALM protein.

In Drosophila, the SALM protein is involved in the organization and maturation of synapses, as well as the modulation of synaptic strength. It promotes synapse formation by interacting with other synaptic proteins and promoting their localization to specific regions of the synapse. Additionally, the SALM protein is involved in regulating the balance between excitatory and inhibitory synapses, which is important for proper neural circuit function.

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Target Background

Function

Required for the establishment of the posterior-most head and the anterior-most tail segments of the embryo. Probably function as a transcriptional regulator. Could repress the transcription of the tsh gene.

Gene References into Functions

spalt is functionally conserved in Locusta and Drosophila to promote wing growth. PMID: 28300136
critical role of in programming the development of specialized flight muscles PMID: 22280912
identification of the transcription factor Spalt major (Salm) as a master regulator of fibrillar flight muscle fate in Drosophila; salm is necessary and sufficient to induce fibrillar muscle fate. PMID: 22094701
Drosophila Sal is a transcriptional repressors PMID: 21689070
The tracheal primordia are already specified as distinct dorsal and ventral cell populations. This subdivision depends on the activity of the spalt (sal) gene. PMID: 12376110
Spalt and senseless promote terminal R8 photoreceptor differentiation during pupal stages, including the regulation of rhodopsin expression. PMID: 15302602
Data show that two Smad proteins that are genetically required for the activation of the spalt (sal) gene in the wing, collaborate with the Hox protein Ultrabithorax (Ubx) to directly repress sal in the haltere. PMID: 17855427
results suggest that the zinc finger factors encoded by the salm/salr complex play important roles in defining cells of the early wing disc as dorsal body wall cells PMID: 19298807

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Subcellular Location

Nucleus.

Protein Families

Sal C2H2-type zinc-finger protein family

Database Links

KEGG: dme:Dmel_CG6464

STRING: 7227.FBpp0088852

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SALM Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background