UBE2J1 Antibody

Datasheet

Code	CSB-PA896502XA01HU
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) UBE2J1 Polyclonal antibody

Uniprot No.

Q9Y385

Target Names

UBE2J1

Alternative Names

UBE2J1 antibody; NCUBE1 antibody; CGI-76 antibody; HSPC153 antibody; HSPC205 antibody; Ubiquitin-conjugating enzyme E2 J1 antibody; EC 2.3.2.23 antibody; E2 ubiquitin-conjugating enzyme J1 antibody; Non-canonical ubiquitin-conjugating enzyme 1 antibody; NCUBE-1 antibody; Yeast ubiquitin-conjugating enzyme UBC6 homolog E antibody; HsUBC6e antibody

Raised in

Rabbit

Species Reactivity

Homo sapiens (Human)

Immunogen

Recombinant Homo sapiens (Human) UBE2J1 protein

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB (ensure identification of antigen)

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Value-added Deliverables

① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);

Quality Guarantee

① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;

Lead Time

Made-to-order (14-16 weeks)

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function

Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD).

Gene References into Functions

These results suggest that UBE2 family member UBE2J1 can negatively regulate type I IFN expression, thereby promote RNA virus infection. PMID: 30157886
Post-transcriptional regulation of glycoprotein quality control in the endoplasmic reticulum is controlled by the UBC6e. PMID: 27570074
data support a physiological role for HRD1 and UBE2J1 in the homeostatic regulation of MHC class I assembly and expression PMID: 21245296
Ubc6e is phosphorylated in response to endoplasmic reticulum stress PMID: 16720581

Subcellular Location

Endoplasmic reticulum membrane; Single-pass type IV membrane protein.

Protein Families

Ubiquitin-conjugating enzyme family

Database Links

HGNC: 17598

OMIM: 616175

KEGG: hsa:51465

STRING: 9606.ENSP00000451261

UniGene: Hs.163776

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Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Protein processing in endoplasmic reticulum Ubiquitin mediated proteolysis

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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UBE2J1 Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background