Recombinant Human Interleukin-5 protein(IL5) (Active)

In Stock
Code CSB-AP001721HU
Product Type Interleukin
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P05113
Lead Time 5-10 business days
Storage Buffer 0.2 μm filtered 20mM PB, pH 7.5, 3 % trehalose, 0.1 % Tween-80 ,lyophilized
Alias IL-5, Eosinophil differentiation factor, T-cell replacing factor, TRF
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.1 ng/ml, corresponding to a specific activity of >1.0x107 IU/mg.
Purity >98% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence M+IPTEIPTSA LVKETLALLS THRTLLIANE TLRIPVPVHK NHQLCTEEIF QGIGTLESQT VQGGTVERLF KNLSLIKKYI DGQKKKCGEE RRRVNQFLDY LQEFLGVMNT EWIIES
Research Area Immunology
Source E.coli
Gene Names IL5
Expression Region 20-134aa
Tag Info Tag-Free
Mol. Weight 26.5 kDa
Protein Description Full Length of Mature Protein
PubMed ID 3024129; 2824500; 3498940; 2823259; 15489334; 2361960; 2037074; 8483502; 22153509
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Function Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.
Subcellular Location Secreted
Protein Families IL-5 family
Database Links

HGNC: 6016

OMIM: 147850

KEGG: hsa:3567

STRING: 9606.ENSP00000231454

UniGene: Hs.2247

Pathway Jak-STAT signaling pathway
Fc epsilon RI signaling pathway
Hematopoietic cell lineage
IL-17 signaling pathway
T cell receptor signaling pathway
Th1 and Th2 cell differentiation

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