Code | CSB-MA916751 |
Size | US$166 |
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Application | Recommended Dilution |
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IHC | 1:20-1:200 |
The production of CR2 monoclonal antibody involves immunizing mice with the synthesized peptide derived from human CD21 protein. The hybridoma cells produced by fusing mouse B cells with myeloma cells are screened for CR2 antibody production. The CR2 monoclonal antibody was affinity-purified from mouse ascites by affinity-chromatography using a specific immunogen. It is suitable for recognizing human CR2 protein in ELISA and IHC applications.
CR2, also known as CD21, is a membrane-bound protein that is primarily expressed on the surface of B-cells. Its main function is to bind to and process complement-coated antigens, facilitating their presentation to T-cells and thus initiating an immune response. Additionally, CD21 also serves as a receptor for the Epstein-Barr virus, playing a role in viral entry and infection.
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