HSP90AA1 Monoclonal Antibody

Datasheet
Code CSB-MA080274
Product Type Monoclonal Antibody
Size US$167
Uniprot No. P07900
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunogen Recombinant Protein
Raised in Mouse
Species Reactivity Human,Mouse,Rat
Tested Applications ELISA,WB;Recommended dilution:WB:1:500-1:5000
Form Liquid
Conjugate Non-conjugated
Storage Buffer PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Isotype IgG
Alias HSP90 α
Immunogen Species Homo sapiens (Human)
Gene Names HSP90AA1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity which is essential for its chaperone activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function
Subcellular Location Nucleus, Cytoplasm, Melanosome, Cell membrane
Protein Families Heat shock protein 90 family
Database Links

HGNC: 5253

OMIM: 140571

KEGG: hsa:3320

STRING: 9606.ENSP00000335153

UniGene: Hs.525600

Pathway Estrogen signaling pathway
PI3K-Akt signaling pathway
Necroptosis
Protein processing in endoplasmic reticulum
Antigen processing and presentation
IL-17 signaling pathway
NOD-like receptor signaling pathway
Th17 cell differentiation

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