Product Details

Purity

≥ 95% as determined by SDS-PAGE.

Endotoxin

≤10 EU/mg by the LAL method

Activity

Determined by its ability to stimulate the proliferation of Nb2-11 cells. Expected ED50 ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 10 7 units/mg

Target Names

Uniprot No.

P01241

Alternative Names

GH1;Somatotropin;Growth hormone;GH;GH-N;Growth hormone 1;Pituitary growth hormone

Species

Homo sapiens (Human)

Source

Mammalian cell

Expression Region

27-217aa

Target Protein Sequence

FPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF

Mol. Weight

22.0 kDa

Protein Length

Full Length of Mature Protein

Tag Info

Tag free

Form

Lyophilized
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.

Buffer

Lyophilized from a 0.2 μm filtered solution containing 10mM PB

Reconstitution

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.

Troubleshooting and FAQs

Protein FAQs

Storage Condition

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.

Shelf Life

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Lead Time

3-7 business days

Notes

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Datasheet & COA

Please contact us to get it.

Description

Growth hormone orchestrates anabolic metabolism, linear growth, and immune modulation through the GH receptor, making authentic recombinant material essential for dissecting these pleiotropic pathways. This tag-free protein spans the complete mature sequence (aa 27–217) and demonstrates potent mitogenic activity in Nb2-11 lymphoma cells with an ED50 ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 × 10⁷ units/mg—performance that supports receptor binding competition assays, cell-based signaling studies measuring cAMP or STAT5 activation, and in vivo pharmacology in metabolic disease models. Endotoxin levels ≤ 10 EU/mg align with standards expected in animal studies where inflammatory confounders must be minimized. Purity exceeding 95% by SDS-PAGE, combined with the validated bioactivity, provides a suitable basis for antibody development, immunoassay calibration, and structure-function investigations requiring a homogeneous, biologically competent reference standard.

Code	CSB-MP009407HU-WD
Abbreviation	Recombinant Human GH protein (Active)
MSDS	MSDS Datasheet
Size	Inquiry
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Image	(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Recombinant Human Somatotropin (GH1) (Active)

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