Recombinant Human Trefoil factor 3 protein(TFF3) (Active)

In Stock
Code CSB-AP000361HU
Product Type Other
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. Q07654
Lead Time 5-10 business days
Storage Buffer 0.2 μm filtered 20 mM PB, pH 7.4, 150mM NaCl ,lyophilized
Alias Intestinal trefoil factor, Polypeptide P1.B, hP1.B
Species Homo sapiens (Human)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a chemotaxis bioassay using human MCF-7 cells is less than 10 μg/ml, corresponding to a specific activity of >100 IU/mg.
Purity >97% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence EEYVGLSANQ CAVPAKDRVD CGYPHVTPKE CNNRGCCFDS RIPGVPWCFK PLQEAECTF
Research Area Signal Transduction
Source E.coli
Gene Names TFF3
Expression Region 22-80aa
Tag Info Tag-Free
Mol. Weight 13.2 kDa
Protein Description Full Length of Mature Protein
PubMed ID 8346203; 9070946; 10950923; 10830953; 15489334; 14637006; 8454642; 15340161; 19670903; 10824705; 11694446; 18209; 14690424
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Function Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).
Subcellular Location Secreted, extracellular space, extracellular matrix, Cytoplasm
Tissue Specificity Expressed in goblet cells of the intestines and colon (at protein level). Expressed by goblet cells of small and large intestinal epithelia and also by the uterus. Also expressed in the hypothalamus where it is detected in paraventricular, periventricular
Database Links

HGNC: 11757

OMIM: 600633

KEGG: hsa:7033

STRING: 9606.ENSP00000430690

UniGene: Hs.82961

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