TFF3

TFF3, or trefoil factor 3 (alias intestinal trefoil factor, ITF), is a secreted peptide of the trefoil family. It maintains gastrointestinal (GI) mucosal barrier integrity—via disulfide-linked dimers or interactions with mucin glycoproteins, it enhances mucosa protection, promotes epithelial cell migration/proliferation, and repairs damage from chemicals or mechanical stress.
TFF3 signals through EGFR and PI3K/Akt pathways. Dysregulation links to inflammatory bowel disease (IBD), colorectal cancer, and gastroesophageal reflux disease (GERD). As a therapeutic target, TFF3-based therapies for mucosal injury are under exploration; its expression also serves as a biomarker for GI disease severity.

Validated Data

TFF3 Monoclonal Antibody (CSB-MA0234331A0m)

Validated Data

Immunohistochemical of paraffin-embedded human colon cancer using CSB-MA0234331A0m at dilution of 1:50

Immunofluorescent analysis of MCF-7 cells using CSB-MA0234331A0m at dilution of 1:50 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Mouse IgG(H+L)

Human Trefoil factor 3(TFF3) ELISA kit (CSB-EL023433HU)

Validated Data

Code: CSB-EL023433HU

Size: 96T,5×96T,10×96T

Sensitivity: 0.078 ng/ml.

Detection Range: 0.312 ng/ml-20 ng/ml.

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following TFF3 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

TFF3 Antibodies

TFF3 Proteins

TFF3 ELISA Kits

TFF3 Antibodies

TFF3 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA11935D0Rb	TFF3 Antibody, Biotin conjugated	Human	ELISA
CSB-PA11935C0Rb	TFF3 Antibody, FITC conjugated	Human
CSB-PA11935A0Rb	TFF3 Antibody	Human	ELISA
CSB-PA023433YD01HU	TFF3 Antibody, Biotin conjugated	Human	ELISA
CSB-PA023433YA01HU	TFF3 Antibody	Human	ELISA
CSB-MA0234331A0m	TFF3 Monoclonal Antibody	Human	ELISA, IHC, IF
CSB-PA038921	TFF3 Antibody	Human	ELISA,IHC
CSB-PA069176	TFF3 Antibody	Human	ELISA,WB,IHC
CSB-PA023433LA01HU	TFF3 Antibody	Human	ELISA, IHC
CSB-PA023433LB01HU	TFF3 Antibody, HRP conjugated	Human	ELISA
CSB-PA023433LC01HU	TFF3 Antibody，FITC conjugated	Human
CSB-PA023433LD01HU	TFF3 Antibody， Biotin conjugated	Human	ELISA

TFF3 Proteins

TFF3 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP023433HU	Recombinant Human Trefoil factor 3 (TFF3),partial	Yeast
CSB-AP000361HU	Recombinant Human Trefoil factor 3 protein (TFF3)	E.Coli
CSB-EP023433HU	Recombinant Human Trefoil factor 3 (TFF3),partial	E.coli

TFF3 ELISA Kit

TFF3 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL023433HU	Human Trefoil factor 3(TFF3) ELISA kit	serum, plasma, tissue homogenates.	0.078 ng/ml.

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TFF3

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