Recombinant Mouse Ly6/PLAUR domain-containing protein 3 (Lypd3) (Active)

Lypd3, a GPI-anchored protein implicated in metastasis and cancer progression, presents challenges for functional studies due to its membrane association and post-translational modifications. This full-length mature protein (aa 33–343) demonstrates specific antibody recognition in functional ELISA, achieving an EC50 of 2.143–2.783 ng/mL when immobilized at 2 μg/mL and probed with anti-LYPD3 recombinant antibody, confirming proper folding and epitope accessibility. Mammalian expression preserves the native glycosylation patterns critical for Lypd3 structure, supporting its use in antibody screening campaigns, epitope mapping studies, and as a positive control in binding assays investigating Lypd3 interactions with candidate ligands or therapeutic antibodies. The protein meets quality thresholds commonly required for cell-based functional assays, with purity exceeding 95% by SDS-PAGE and endotoxin levels below 1.0 EU/μg.