ALPK1 Antibody

Code CSB-PA001628GA01HU
Size US$685
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Product Details

Uniprot No. Q96QP1
Target Names ALPK1
Alternative Names 8430410J10Rik antibody; Alpha protein kinase 1 antibody; Alpha-protein kinase 1 antibody; ALPK1 antibody; ALPK1_HUMAN antibody; Chromosome 4 kinase antibody; LAK antibody; Lymphocyte alpha kinase antibody; Lymphocyte alpha protein kinase antibody; Lymphocyte alpha-protein kinase antibody; RGD1304613 antibody
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Human ALPK1
Immunogen Species Homo sapiens (Human)
Isotype IgG
Purification Method Antigen Affinity purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications ELISA,WB,IHC
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation.
Gene References into Functions
  1. In lung and colorectal cancer tissues, the ALPK1 RNA level of the normal part was higher than that of the tumor part. these findings suggested that ALPK1 might play a vital role in cancer development. PMID: 27283888
  2. ALPK1 is a kinase that participates in the regulation of Golgi-derived TNF-alpha trafficking through myosin IIA phosphorylation in the inflammation of gout. PMID: 27169898
  3. ERN1 and ALPK1 inhibit differentiation of bi-potential tumor-initiating cells in human triple negative breast cancer. PMID: 27829216
  4. these results clearly show that ALPK1 is a master regulator of innate immunity against both invasive and extracellular gram-negative bacteria. PMID: 28222186
  5. findings suggest that among genes in a gout-susceptibility locus, not ALPK1 but ABCG2 could be important as a gout-susceptible gene PMID: 25326865
  6. single nucleotide polymorphisms in the alpha-protein kinase 1 (ALPK1) gene are associated with gout in Han Chinese Taiwanese. PMID: 23569188
  7. ALPK1 may be a susceptibility gene for chronic kidney disease in such individuals with diabetes mellitus. PMID: 23539754
  8. ALPK1 is a gout-susceptible gene involved in Monosodium urate monohydrate-induced inflammatory responses and may contribute to the development of gout by enhancing the inflammatory responses via the MAP kinase pathway PMID: 21822924
  9. Transposon-inserted Alpk1 homozygous mutant mice display severe defects in motor coordination in a series of behavioral analyses. PMID: 21208416
  10. the phosphorylation of myosin I by ALPK1 is an essential process in the apical trafficking of raft-associated sucrose-isomaltase PMID: 15883161

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Protein Families Protein kinase superfamily, Alpha-type protein kinase family, ALPK subfamily
Tissue Specificity Highly expressed in liver.
Database Links

HGNC: 20917

OMIM: 607347

KEGG: hsa:80216

STRING: 9606.ENSP00000177648

UniGene: Hs.652825

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