AOAH Antibody

Datasheet

Code	CSB-PA001853LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in:Mouse Brain tissue lysate All lanes: AOAH antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 66 kDa Observed band size: 66 kDa IHC image of CSB-PA001853LA01HU diluted at 1:100 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) AOAH Polyclonal antibody

Uniprot No.

P28039

Target Names

AOAH

Alternative Names

Acyloxyacyl hydrolase (neutrophil) antibody; Acyloxyacyl hydrolase large subunit antibody; AOAH antibody; AOAH_HUMAN antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Acyloxyacyl hydrolase protein (180-254AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The AOAH Antibody (Product code: CSB-PA001853LA01HU) is Non-conjugated. For AOAH Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA001853LB01HU	AOAH Antibody, HRP conjugated	ELISA
FITC	CSB-PA001853LC01HU	AOAH Antibody, FITC conjugated
Biotin	CSB-PA001853LD01HU	AOAH Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

Application:ELISA, Mouse(WB),Human(IHC)

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:50-1:200

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

CUSABIO produces the product (CSB-PA623900LA01HU) by immunizing rabbits with the peptide corresponding to amino acids 131-332 of the recombinant human LRP8. The anti-LRP8 antibody is eventually purified from rabbit antiserum by protein G affinity chromatography. Its purity is greater than 95%. It occurs as an unconjugated IgG. And it only reacts with human LRP8 protein. This LRP8 polyclonal antibody is suitable for the detection of LRP8 protein in ELISA, WB, and IF applications.

The LRP8 protein, also known as apolipoprotein E receptor 2 (APOER2), regulates the uptake and clearance of lipoproteins and mediates signaling events in response to extracellular ligands, with important implications for brain development and function, as well as for metabolic disorders and neurodegenerative diseases.

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Target Background

Function

Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides. By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses. In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria.

Gene References into Functions

analysis of AOAH function through its crystal structure and complex with lipopolysaccharide PMID: 29343645
AOAH - Gene involved in innate immunity that have been associated with Chronic Rhinosinusitis. PMID: 27888910
AOAH rs60023210 variants may be associated with carotid intima-media thickness at bifurcation. PMID: 26319989
Polymorphisms in RYBP and AOAH genes are associated with chronic rhinosinusitis in a Chinese population. PMID: 22723975

Subcellular Location

Secreted. Cytoplasmic vesicle.

Database Links

HGNC: 548

OMIM: 102593

KEGG: hsa:313

STRING: 9606.ENSP00000258749

UniGene: Hs.488007

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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