AP1B1 Antibody

Code CSB-PA001860GA01HU
Size US$685
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Product Details

Uniprot No. Q10567
Target Names AP1B1
Alternative Names Adaptin; beta 2 (beta) antibody; Adaptor protein complex AP-1 subunit beta-1 antibody; Adaptor related protein complex 1; beta 1 subunit antibody; Adaptor related protein complex 2; beta 1 subunit antibody; Adaptor-related protein complex 1 subunit beta-1 antibody; ADTB1 antibody; ADTB2 antibody; AP 1 complex subunit beta 1 antibody; AP 2 complex subunit beta 1 antibody; AP-1 complex subunit beta-1 antibody; AP1 Beta antibody; AP1B1 antibody; AP1B1_HUMAN antibody; AP2 Beta antibody; AP2B1 antibody; Beta-1-adaptin antibody; Beta-adaptin 1 antibody; Beta1 adaptin antibody; Beta2 adaptin antibody; CLAPB1 antibody; CLAPB2 antibody; Clathrin assembly protein complex 1 beta large chain antibody; Golgi adaptor HA1/AP1 adaptin beta subunit antibody
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Human AP1B1
Immunogen Species Homo sapiens (Human)
Isotype IgG
Purification Method Antigen Affinity purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications ELISA,WB,IF
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
Gene References into Functions
  1. both ubiquitous (AP-1A) and epithelium-specific (AP-1B) forms of the tetrameric clathrin adaptor AP-1 are capable of carrying out basolateral sorting of ClC-2. PMID: 25739457
  2. AP1B regulates basolateral EGFR membrane delivery predominantly in the biosynthetic route in MDCK cells monolayers. PMID: 23205726
  3. The conclude that in addition to its role in endocytosis, ARH cooperates with AP-1B in basolateral exocytosis of LDLR from recycling endosomes. PMID: 21444685
Subcellular Location Golgi apparatus, Cytoplasmic vesicle, clathrin-coated vesicle membrane, Peripheral membrane protein, Cytoplasmic side
Protein Families Adaptor complexes large subunit family
Tissue Specificity Widely expressed.
Database Links

HGNC: 554

OMIM: 600157

KEGG: hsa:162

STRING: 9606.ENSP00000350199

UniGene: Hs.368794

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