AP1B1 Antibody

Code CSB-PA062845
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA062845(AP1B1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA062845(AP1B1 Antibody) at dilution 1/70, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
AP1B1
Alternative Names
Adaptin; beta 2 (beta) antibody; Adaptor protein complex AP-1 subunit beta-1 antibody; Adaptor related protein complex 1; beta 1 subunit antibody; Adaptor related protein complex 2; beta 1 subunit antibody; Adaptor-related protein complex 1 subunit beta-1 antibody; ADTB1 antibody; ADTB2 antibody; AP 1 complex subunit beta 1 antibody; AP 2 complex subunit beta 1 antibody; AP-1 complex subunit beta-1 antibody; AP1 Beta antibody; AP1B1 antibody; AP1B1_HUMAN antibody; AP2 Beta antibody; AP2B1 antibody; Beta-1-adaptin antibody; Beta-adaptin 1 antibody; Beta1 adaptin antibody; Beta2 adaptin antibody; CLAPB1 antibody; CLAPB2 antibody; Clathrin assembly protein complex 1 beta large chain antibody; Golgi adaptor HA1/AP1 adaptin beta subunit antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthetic peptide of Human AP1B1
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.
Gene References into Functions
  1. both ubiquitous (AP-1A) and epithelium-specific (AP-1B) forms of the tetrameric clathrin adaptor AP-1 are capable of carrying out basolateral sorting of ClC-2. PMID: 25739457
  2. AP1B regulates basolateral EGFR membrane delivery predominantly in the biosynthetic route in MDCK cells monolayers. PMID: 23205726
  3. The conclude that in addition to its role in endocytosis, ARH cooperates with AP-1B in basolateral exocytosis of LDLR from recycling endosomes. PMID: 21444685
Subcellular Location
Golgi apparatus. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex.
Protein Families
Adaptor complexes large subunit family
Tissue Specificity
Widely expressed.
Database Links

HGNC: 554

OMIM: 600157

KEGG: hsa:162

STRING: 9606.ENSP00000350199

UniGene: Hs.368794

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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