CD47|Proteinase K|EGFR|BCMA|PD-L1|CD276|ACE2|TMPRSS2|Exosome Isolation Kits
Code | CSB-PA123263 |
Size | US$299 |
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Have Questions? | Leave a Message or Start an on-line Chat |
Uniprot No. | Q92888 | ||||||
Target Names | ARHGEF1 | ||||||
Alternative Names | 115 kD protein antibody; 115 kDa guanine nucleotide exchange factor antibody; ARHG1_HUMAN antibody; ARHGEF 1 antibody; ARHGEF1 antibody; GEF 1 antibody; GEF1 antibody; LBCL 2 antibody; LBCL2 antibody; LSC antibody; Lsc homolog antibody; p115 RhoGEF antibody; p115-RhoGEF antibody; p115RhoGEF antibody; Rho guanine nucleotide exchange factor (GEF) 1 antibody; Rho guanine nucleotide exchange factor 1 antibody; Sub1.5 antibody | ||||||
Raised in | Rabbit | ||||||
Species Reactivity | Human,Mouse,Rat | ||||||
Immunogen | Fusion protein of Human ARHGEF1 | ||||||
Immunogen Species | Homo sapiens (Human) | ||||||
Conjugate | Non-conjugated | ||||||
Isotype | IgG | ||||||
Purification Method | Antigen affinity purification | ||||||
Concentration | It differs from different batches. Please contact us to confirm it. | ||||||
Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | ||||||
Form | Liquid | ||||||
Tested Applications | ELISA,IHC | ||||||
Recommended Dilution |
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Protocols | ELISA Protocol Immunohistochemistry (IHC) Protocol |
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Troubleshooting and FAQs | Antibody FAQs | ||||||
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||
Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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Function | Seems to play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13) subunits. Acts as GTPase-activating protein (GAP) for GNA12 and GNA13, and as guanine nucleotide exchange factor (GEF) for RhoA GTPase. Activated G alpha 13/GNA13 stimulates the RhoGEF activity through interaction with the RGS-like domain. This GEF activity is inhibited by binding to activated GNA12. Mediates angiotensin-2-induced RhoA activation. |
Gene References into Functions |
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Subcellular Location | Cytoplasm, Membrane |
Tissue Specificity | Ubiquitously expressed. |
Database Links |
HGNC: 681 OMIM: 601855 KEGG: hsa:9138 STRING: 9606.ENSP00000337261 UniGene: Hs.631550 |