ARL2BP Antibody

Datasheet
Code CSB-PA918867
Product Type Polyclonal Antibody
Size US$297
Uniprot No. Q9Y2Y0
Image
  • Western blot analysis of extracts from A549 cells, using ARL2BP antibody.
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunogen Synthesized peptide derived from internal of Human ARL2BP.
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Specificity The antibody detects endogenous levels of total ARL2BP protein
Tested Applications ELISA,WB;WB:1:500-1:3000
Relevance Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.

Sharer J.D., J. Biol. Chem. 274:27553-27561(1999).
The MGC Project Team; Genome Res. 14:2121-2127(2004).
Van Valkenburgh H., J. Biol. Chem. 276:22826-22837(2001)
Form Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality Polyclonal
Alias ADP-ribosylation factor-like 2 binding; AR2BP; Arf-like 2 binding protein BART1; ARL2BP; BART1
Immunogen Species Homo sapiens (Human)
Target Names ARL2BP
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2.
Involvement in disease Retinitis pigmentosa with or without situs inversus (RPSI)
Subcellular Location Cytoplasm, Mitochondrion intermembrane space, Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, Nucleus, Cytoplasm, cytoskeleton, spindle, Cytoplasm, cytoskeleton, cilium basal body
Protein Families ARL2BP family
Tissue Specificity Expressed in retina pigment epithelial cells (at protein level). Widely expressed.
Database Links

HGNC: 17146

OMIM: 615407

KEGG: hsa:23568

STRING: 9606.ENSP00000219204

UniGene: Hs.632873

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