ATG4C Antibody

Datasheet

Code	CSB-PA097577
Size	US$297
	Order now
Image	Western blot analysis of extracts from K562 cells and COS7 cells, using ATG4C antibody. Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using ATG4C antibody. Immunofluorescence analysis of HuvEc cells, using ATG4C antibody.
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) ATG4C Polyclonal antibody

Uniprot No.

Q96DT6

Target Names

ATG4C

Alternative Names

APG4 autophagy 4 homolog C (S. cerevisiae) antibody; APG4 autophagy 4 homolog C antibody; APG4 C antibody; APG4-C antibody; APG4C antibody; ATG 4C antibody; ATG4 autophagy related 4 homolog C (S. cerevisiae) antibody; ATG4 autophagy related 4 homolog C antibody; Atg4c antibody; ATG4C_HUMAN antibody; AUT (S. cerevisiae) like 1; cysteine endopeptidase antibody; AUT like 1; cysteine endopeptidase (S. cerevisiae) antibody; AUT like 1; cysteine endopeptidase antibody; AUT like 3 cysteine endopeptidase antibody; AUT-like 3 cysteine endopeptidase antibody; AUTL1 antibody; AUTL3 antibody; Autophagin 3 antibody; Autophagin-3 antibody; Autophagy related 4C cysteine peptidase antibody; Autophagy related cysteine endopeptidase 3 antibody; Autophagy related protein 4 homolog C antibody; Autophagy-related cysteine endopeptidase 3 antibody; Autophagy-related protein 4 homolog C antibody; Cysteine protease ATG4C antibody; EC 3.4.22 antibody; FLJ14867 antibody; OTTHUMP00000010715 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthesized peptide derived from internal of Human ATG4C.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,WB,IHC,IF

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:3000
IHC	1:50-1:100
IF	1:100-1:500

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.

Gene References into Functions

association between SNPs and Kashin-Beck disease PMID: 27742532
We demonstrate that, in breast cancer cells, ATM and ATG4C are essential drivers of mammosphere formation, suggesting that their targeting may improve current approaches to eradicate breast cancer cells with a stem-like phenotype. PMID: 28423511
miR-376b controls autophagy by directly regulating intracellular levels of two key autophagy proteins, ATG4C and BECN1. PMID: 22248718

Subcellular Location

Cytoplasm.

Protein Families

Peptidase C54 family

Database Links

HGNC: 16040

OMIM: 611339

KEGG: hsa:84938

STRING: 9606.ENSP00000322159

UniGene: Hs.7353

Promotions

CUSABIO Premium Active Proteins 20% OFF SALE

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Autophagy

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：
Please enter the characters shown. Click the image to refresh if unclear.

Place an order now

I. Product details

Product name *

Code *

Size *

Quantity *

Message

II. Contact details

Name *

Email address *

Company/Organization

Phone

III. Ship To

Address *

City *

State/Province *

Zip/Post code *

Country *

Attn Name *

Phone# *

IV. Bill To Same as Shipping Address