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Cysteine protease ATG4C is a protein in humans that is encoded by ATG4C gene. Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
The following ATG4C reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
ATG4C Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA002291GA01HU | ATG4C Antibody |
Human,Mouse | ELISA,WB,IHC,IF |
| CSB-PA097577 | ATG4C Antibody |
Human,Mouse | ELISA,WB,IHC,IF |
| CSB-PA836199ESR2HU | ATG4C Antibody |
Human, Mouse | ELISA, WB, IHC |
| CSB-PA070056 | ATG4C Antibody |
Human,Monkey | WB, IHC, IF, ELISA |
| CSB-PA555140 | ATG4C Antibody |
Human,Mouse | ELISA,WB,IHC |
| CSB-PA195861 | ATG4C Antibody |
Human,Mouse | ELISA,WB,IHC |
| CSB-PA732174 | ATG4C Antibody |
Human,Mouse,Rat | IHC, ELISA |
| CSB-PA836199LA01HU | ATG4C Antibody |
Human | ELISA, IHC, IF |
ATG4C Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP715017XBF CSB-EP715017XBF CSB-BP715017XBF CSB-MP715017XBF CSB-EP715017XBF-B |
Recombinant Xenopus tropicalis Cysteine protease ATG4C (atg4c) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ATG4C Proteins for Xenopus laevis (African clawed frog)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP723038XBE CSB-EP723038XBE CSB-BP723038XBE CSB-MP723038XBE CSB-EP723038XBE-B |
Recombinant Xenopus laevis Cysteine protease ATG4C (atg4c) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ATG4C Proteins for Mus musculus (Mouse)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP768936MO CSB-EP768936MO CSB-BP768936MO CSB-MP768936MO CSB-EP768936MO-B |
Recombinant Mouse Cysteine protease ATG4C (Atg4c) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
ATG4C Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP836199HU CSB-EP836199HU CSB-BP836199HU CSB-MP836199HU CSB-EP836199HU-B |
Recombinant Human Cysteine protease ATG4C (ATG4C) |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
Cysteine protease ATG4C is a protein in humans that is encoded by the ATG4C gene. Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. It is not essential for autophagy development under normal conditions but is required for a proper autophagic response under stressful conditions such as prolonged starvation (By similarity). ATG4C cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. It has also an activity of the delipidating enzyme for the PE-conjugated forms.
