ATL2 Antibody

Code CSB-PA836776LA01HU
Size US$166
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  • Western blot
    All lanes: ATL2 antibody at 1µg/ml
    Lane 1: HepG2 whole cell lysate
    Lane 2: MCF-7 whole cell lysate
    Lane 3: HL60 whole cell lysate
    Lane 4: K562 whole cell lysate
    Lane 5: U251 whole cell lysate
    Lane 6: A549 whole cell lysate
    Lane 7: A431 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 67, 47, 66, 65 kDa
    Observed band size: 67 kDa
  • Immunofluorescent analysis of HepG2 cells using CSB-PA836776LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ATL2 Polyclonal antibody
Uniprot No.
Target Names
ATL2
Alternative Names
ATL2; ARL6IP2; Atlastin-2; ADP-ribosylation factor-like protein 6-interacting protein 2; ARL-6-interacting protein 2; Aip-2
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Atlastin-2 protein (1-300AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The ATL2 Antibody (Product code: CSB-PA836776LA01HU) is Non-conjugated. For ATL2 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA836776LB01HU ATL2 Antibody, HRP conjugated ELISA
FITC CSB-PA836776LC01HU ATL2 Antibody, FITC conjugated
Biotin CSB-PA836776LD01HU ATL2 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
GTPase tethering membranes through formation of trans-homooligomers and mediating homotypic fusion of endoplasmic reticulum membranes. Functions in endoplasmic reticulum tubular network biogenesis.
Gene References into Functions
  1. These results suggest that the three ATLs have different capacities to mediate endoplasmic reticulum fusion, with ATL1 being the strongest and ATL3 being the weakest. PMID: 25773277
  2. The role of GTP hydrolysis in the ATL2 fusion mechanism also needs to be tempered by the uncertainty of whether the behavior of the ATL2 soluble domain, observed herein, reflects the behavior of the full-length, membrane-anchored protein. PMID: 22065636
  3. A family of human GTPases, atlastin-2 and -3 that are closely related to atlastin-1 are described. PMID: 18270207
Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Protein Families
TRAFAC class dynamin-like GTPase superfamily, GB1/RHD3-type GTPase family, GB1 subfamily
Tissue Specificity
Expressed in peripheral tissues (at protein level).
Database Links

HGNC: 24047

OMIM: 609368

KEGG: hsa:64225

STRING: 9606.ENSP00000368237

UniGene: Hs.594950

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