ATP5F1 Antibody

Code CSB-PA020295
Size US$119
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  • Western Blot analysis of 3T3 cells using ATP5F1 Polyclonal Antibody
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Product Details

Uniprot No.
Target Names
Alternative Names
AT5F1_HUMAN antibody; ATP synthase B chain mitochondrial antibody; ATP synthase subunit b antibody; ATP synthase subunit b mitochondrial antibody; ATP synthase; H+ transporting; mitochondrial F0 complex; subunit b; antibody; ATP synthase; H+ transporting; mitochondrial F0 complex; subunit b; isoform 1 antibody; ATP synthase; H+ transporting; mitochondrial F0 complex; subunit B1 antibody; ATP5F1 antibody; ATPase subunit b antibody; Cell proliferation inducing protein 47 antibody; H+ ATP synthase subunit b antibody; MGC24431 antibody; mitochondrial antibody; PIG47 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the Internal region of Human ATP5F1.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:10000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements.
Gene References into Functions
  1. Down-regulation of mitochondrial ATPase by hypermethylation mechanism in chronic myeloid leukemia is associated with multidrug resistance. PMID: 20038517
  2. Nitration of tyrosine residues 368 and 345 in the beta-subunit elicits FoF1-ATPase activity loss. PMID: 19650768
Subcellular Location
Mitochondrion. Mitochondrion inner membrane.
Protein Families
Eukaryotic ATPase B chain family
Database Links

HGNC: 840

OMIM: 603270

KEGG: hsa:515

STRING: 9606.ENSP00000358737

UniGene: Hs.514870

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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