AXIN2 Antibody, Biotin conjugated

Datasheet
Code CSB-PA897472OD01HU
Size US$299
Uniprot No. Q9Y2T1
Immunogen Peptide sequence from Human Axin-2 protein (56-73AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA
Relevance Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B (By similarity).
Form Liquid
Conjugate Biotin
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method Antigen Affinity Purified
Isotype IgG
Clonality Polyclonal
Alias Axin-2 (Axin-like protein) (Axil) (Axis inhibition protein 2) (Conductin), AXIN2
Immunogen Species Human
Protocols ELISA Protocol
Research Area Cell Biology
Target Names AXIN2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B (By similarity).
Involvement in disease Colorectal cancer (CRC); Oligodontia-colorectal cancer syndrome (ODCRCS)
Subcellular Location Cytoplasm
Tissue Specificity Expressed in brain and lymphoblast.
Database Links

HGNC: 904

OMIM: 114500

KEGG: hsa:8313

STRING: 9606.ENSP00000302625

UniGene: Hs.156527

Pathway Hippo signaling pathway
Wnt signaling pathway
Signaling pathways regulating pluripotency of stem cells

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