AXIN2 Antibody

Datasheet
Code CSB-RA897472A0HU
Size US$350
Uniprot No. Q9Y2T1
Protocols ELISA Protocol
Immunogen A synthesized peptide derived from human AXIN2
Species Reactivity Human
Tested Applications ELISA
Relevance Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B (By similarity).
Form Liquid
Conjugate Non-conjugated
Storage Buffer Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method Affinity-chromatography
Isotype Rabbit IgG
Clonality Monoclonal
Alias Axin-2, Axin-like protein, Axil, Axis inhibition protein 2, Conductin, AXIN2
Immunogen Species Human
Research Area Cell Biology
Gene Names AXIN2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Inhibitor of the Wnt signaling pathway. Down-regulates beta-catenin. Probably facilitate the phosphorylation of beta-catenin and APC by GSK3B (By similarity).
Involvement in disease Colorectal cancer (CRC); Oligodontia-colorectal cancer syndrome (ODCRCS)
Subcellular Location Cytoplasm
Tissue Specificity Expressed in brain and lymphoblast.
Database Links

HGNC: 904

OMIM: 114500

KEGG: hsa:8313

STRING: 9606.ENSP00000302625

UniGene: Hs.156527

Pathway Hippo signaling pathway
Wnt signaling pathway
Signaling pathways regulating pluripotency of stem cells

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