BIRC8 Antibody

Code CSB-PA002709GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
BIRC8
Alternative Names
Baculoviral IAP repeat containing 8 antibody; Baculoviral IAP repeat containing protein 8 antibody; Baculoviral IAP repeat-containing protein 8 antibody; BIRC 8 antibody; BIRC8 antibody; BIRC8 protein antibody; BIRC8_HUMAN antibody; hILP 2 antibody; hILP2 antibody; IAP like protein 2 antibody; IAP-like protein 2 antibody; ILP 2 antibody; ILP-2 antibody; Inhibitor of apoptosis like protein 2 antibody; Inhibitor of apoptosis-like protein 2 antibody; Testis specific inhibitor of apoptosis antibody; Testis-specific inhibitor of apoptosis antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Human BIRC8
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Protects against apoptosis mediated by BAX.
Gene References into Functions
  1. High ILP-2 expression is associated with breast cancer. PMID: 30106449
  2. Fumonisin B1 caused dose-dependent increase in BIRC-8/ILP-2 mRNA and protein expression in HepG2 cells to inhibit apoptosis. PMID: 25800559
  3. results indicate that ILP-2 is a novel breast cancer biomarker in the peripheral blood. PMID: 23222679
  4. increased expression with progression of chronic myeloid leukaemia PMID: 24266799
  5. role in preventing shear-stress induced endothelial cell apoptosis via negative regulation of caspase-3 PMID: 12372615
  6. ILP2 is an unstable protein, and cannot inhibit caspase 9 in a physiological way on its own; possibly ILP2 requires assistance from unidentified cellular factors to be an effective inhibitor of apoptosis in vivo PMID: 15485395

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Subcellular Location
Cytoplasm.
Protein Families
IAP family
Tissue Specificity
Testis specific in normal tissues.
Database Links

HGNC: 14878

KEGG: hsa:112401

STRING: 9606.ENSP00000412957

UniGene: Hs.348263

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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