BMP8A Antibody

Code CSB-PA256187
Size US$297Purchase it in Cusabio online store
(only available for customers from the US)
Image
  • Western blot analysis of extracts from COLO cells, using BMP8A antibody.
  • Immunofluorescence analysis of A549 cells, using BMP8A antibody.
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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) BMP8A Polyclonal antibody
Uniprot No. Q7Z5Y6
Target Names BMP8A
Alternative Names BMP-8A antibody; BMP8 antibody; Bmp8a antibody; BMP8A_HUMAN antibody; Bone morphogenetic protein 8A antibody; FLJ14351 antibody; FLJ45264 antibody; OP 2 antibody; Osteogenic protein 2 antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Synthesized peptide derived from C-terminal of Human BMP8A.
Immunogen Species Homo sapiens (Human)
Clonality Polyclonal
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration It differs from different batches. Please contact us to confirm it.
Form Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications ELISA,WB,IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
IF 1:100-1:500
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
(From Uniprot)
Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis (By similarity). Signaling protein involved in regulation of thermogenesis and energy balance. Proposed to increase the peripheral response of brown adipose tissue (BAT) to adrenergic stimulation while acting centrally in the hypothalamus to increase sympathetic output to BAT.
Gene References into Functions
  1. Authors found that Bmp8a, but not Bmp8b, was expressed predominantly in the neonatal mouse spermatogonia. Although most BMPs induce activation of SMADs 1, 5, and 8 (SMAD1/5/8), but not SMADs 2 and 3 (SMAD2/3), they found that BMP8A induced signaling through both sets of transcription factors. PMID: 28465413
  2. Observational study of gene-disease association. (HuGE Navigator) PMID: 20424473
  3. Observational study of gene-disease association. (HuGE Navigator) PMID: 20237496
Subcellular Location Secreted
Protein Families TGF-beta family
Database Links

HGNC: 21650

KEGG: hsa:353500

STRING: 9606.ENSP00000327440

UniGene: Hs.472497

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