CA5B Antibody

Code CSB-PA039070
Size US$297
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  • Western blot analysis of extracts from NIH/3T3 cells, using CA5B antibody.
  • Immunofluorescence analysis of MCF-7 cells, using CA5B antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) CA5B Polyclonal antibody
Uniprot No.
Target Names
CA5B
Alternative Names
CA VB antibody; CA-VB antibody; CA5B antibody; CAH5B_HUMAN antibody; Carbonate dehydratase VB antibody; Carbonic anhydrase 5B antibody; Carbonic anhydrase 5B; mitochondrial antibody; Carbonic anhydrase VB antibody; Carbonic anhydrase VB; mitochondrial antibody; mitochondrial antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from internal of Human CA5B.
Immunogen Species
Homo sapiens (Human)
Clonality
Polyclonal
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
ELISA,WB,IHC,IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
IHC 1:50-1:200
IF 1:100-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Reversible hydration of carbon dioxide.
Gene References into Functions
  1. In 10 of 96 patients, mutations in CA5A were identified on both alleles but none in CA5B. Exhibiting decreased enzyme activity or thermal stability, all CAVA mutations were proven to cause disease, whereas the three variants showed no relevant effect PMID: 26913920
  2. activators enhanced kcat, with no effect on KM, favoring the RDS in the catalytic cycle; the activation pattern of the two mitochondrial isoforms is very different from each other and as compared to those of the cytosolic isoforms hCA I and II. PMID: 17174092
Subcellular Location
Mitochondrion.
Protein Families
Alpha-carbonic anhydrase family
Tissue Specificity
Strongest expression in heart, pancreas, kidney, placenta, lung, and skeletal muscle. Not expressed in liver.
Database Links

HGNC: 1378

OMIM: 300230

KEGG: hsa:11238

STRING: 9606.ENSP00000314099

UniGene: Hs.653287

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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